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San Francisco Injury Center

The San Francisco Injury Center for Research and Prevention

logo1.gifThe San Francisco Injury Center for Research and Prevention (SFIC) is one of 13 Injury Control Research Centers funded by the National Center for injury Prevention and Control at the Centers for Disease Control and Prevention.  The SFIC was established in 1989 and is located at the San Francisco General Hospital campus of the University of California, San Francisco, School of Medicine.

 The SFIC is a center without walls - bringing together multidisciplinary faculty investigators from throughout the UCSF campus and beyond.  The resulting collaborative efforts in laboratory research, clinical trials and injury prevention research have the potential to improve outcomes for victims of trauma in our region and to influence the field of injury control on a global basis.

Our theme is "Injury Control 2010: Making Changes and Meeting Challenges". Our work builds on our history of successfully conducting high quality scientific research that impacts the care of the severely injured patient, while at the same time focusing on prevention programs driven by local data.

Recent Publications

Bir N, Lafargue M, Howard M, Goolaerts A, Roux J, Carles M, Cohen MJ, Iles KE, Fernández JA, Griffin JH, Pittet JF
Cytoprotective-selective activated protein C attenuates Pseudomonas aeruginosa-induced lung injury in mice.
American journal of respiratory cell and molecular biology, Sep-01-2011; 453: 632-41.  Epub 2011 Jan 21.
Meyer NJ, Li M, Feng R, Bradfield J, Gallop R, Bellamy S, Fuchs BD, Lanken PN, Albelda SM, Rushefski M, Aplenc R, Abramova H, Atochina-Vasserman EN, Beers MF, Calfee CS, Cohen MJ, Pittet JF, Christiani DC, O'Keefe GE, Ware LB, May AK, Wurfel MM, Hakonarson H, Christie JD
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio.
American journal of respiratory and critical care medicine, May-15-2011; 18310: 1344-53.  Epub 2011 Jan 21.
Dicker RA, Lopez DS, Pepper MB, Crane I, Max W
Cost-driven injury prevention: creating an innovative plan to save lives with limited resources.
The Journal of trauma, Apr-01-2011; 704: 985-90.
Brown LM, Kallet RH, Matthay MA, Dicker RA
The influence of race on the development of acute lung injury in trauma patients.
American journal of surgery, Apr-01-2011; 2014: 486-91.  Epub 2010 Sep 15.
Jayaraman S, Ozgediz D, Miyamoto J, Caldwell N, Lipnick MS, Mijumbi C, Mabweijano J, Hsia R, Dicker R
Disparities in injury mortality between Uganda and the United States: comparative analysis of a neglected disease.
World journal of surgery, Mar-01-2011; 353: 505-11.
Moore EE, Knudson MM, Burlew CC, Inaba K, Dicker RA, Biffl WL, Malhotra AK, Schreiber MA, Browder TD, Coimbra R, Gonzalez EA, Meredith JW, Livingston DH, Kaups KL, Kaups KL
Defining the limits of resuscitative emergency department thoracotomy: a contemporary Western Trauma Association perspective.
The Journal of trauma, Feb-01-2011; 702: 334-9.
Roll GR, Lee AY, Royaie K, Visser B, Hanks DK, Knudson MM, Roll FJ
Acquired A amyloidosis from injection drug use presenting with atraumatic splenic rupture in a hospitalized patient: a case report.
Journal of medical case reports, [epublish] 5: 29.
Knudson MM, Cohen MJ, Reidy R, Jaeger S, Bacchetti P, Jin C, Wade CE, Holcomb JB
Trauma, transfusions, and use of recombinant factor VIIa: A multicenter case registry report of 380 patients from the Western Trauma Association.
Journal of the American College of Surgeons, Jan-01-2011; 2121: 87-95.  Epub 2010 Nov 5.
Frith D, Goslings JC, Gaarder C, Maegele M, Cohen MJ, Allard S, Johansson PI, Stanworth S, Thiemermann C, Brohi K
Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations.
Journal of thrombosis and haemostasis : JTH, Sep-01-2010; 89: 1919-25.
Cohen MJ, Serkova NJ, Wiener-Kronish J, Pittet JF, Niemann CU
1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit.
The Journal of trauma, Jul-01-2010; 691: 31-40.
Cohen MJ, Carles M, Brohi K, Calfee CS, Rahn P, Call MS, Chesebro BB, West MA, Pittet JF
Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans.
The Journal of trauma, Jun-01-2010; 686: 1273-8.
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